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Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Migrastatin is a biologically active natural product isolated from Streptomyces that has been shown to inhibit tumor cell migration. Upon completion of the first total synthesis of migrastatin, a number of structurally simplified analogs were prepared. Following extensive in vitro screening, a new g...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174672/ https://ncbi.nlm.nih.gov/pubmed/21808037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015247108 |
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