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Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice
Tumor metastasis is the most common cause of death in cancer patients. Here, we show that two, fully synthetic migrastatin analogues, core macroketone and core macrolactam, are potent inhibitors of metastasis in a murine breast tumor model. Administration of these readily accessible compounds nearly...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC553334/ https://ncbi.nlm.nih.gov/pubmed/15728385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500658102 |
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