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Migrastatin Analogues Target Fascin to Block Tumor Metastasis

Tumor metastasis is the primary cause of death of cancer patients. Development of new therapeutics preventing tumor metastasis is urgently needed. Migrastatin is a natural product secreted by Streptomyces 1,2, and synthesized migrastatin analogues are potent inhibitors of metastatic tumor cell migra...

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書目詳細資料
Main Authors: Chen, Lin, Yang, Shengyu, Jakoncic, Jean, Zhang, J. Jillian, Huang, Xin-Yun
格式: Artigo
語言:Inglês
出版: 2010
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857318/
https://ncbi.nlm.nih.gov/pubmed/20393565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08978
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