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Migrastatin Analogues Target Fascin to Block Tumor Metastasis
Tumor metastasis is the primary cause of death of cancer patients. Development of new therapeutics preventing tumor metastasis is urgently needed. Migrastatin is a natural product secreted by Streptomyces 1,2, and synthesized migrastatin analogues are potent inhibitors of metastatic tumor cell migra...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857318/ https://ncbi.nlm.nih.gov/pubmed/20393565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08978 |
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