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Migrastatin Analogues Target Fascin to Block Tumor Metastasis

Tumor metastasis is the primary cause of death of cancer patients. Development of new therapeutics preventing tumor metastasis is urgently needed. Migrastatin is a natural product secreted by Streptomyces 1,2, and synthesized migrastatin analogues are potent inhibitors of metastatic tumor cell migra...

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Detalhes bibliográficos
Main Authors: Chen, Lin, Yang, Shengyu, Jakoncic, Jean, Zhang, J. Jillian, Huang, Xin-Yun
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857318/
https://ncbi.nlm.nih.gov/pubmed/20393565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08978
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