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Migrastatin Analogues Target Fascin to Block Tumor Metastasis

Tumor metastasis is the primary cause of death of cancer patients. Development of new therapeutics preventing tumor metastasis is urgently needed. Migrastatin is a natural product secreted by Streptomyces 1,2, and synthesized migrastatin analogues are potent inhibitors of metastatic tumor cell migra...

詳細記述

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書誌詳細
主要な著者: Chen, Lin, Yang, Shengyu, Jakoncic, Jean, Zhang, J. Jillian, Huang, Xin-Yun
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857318/
https://ncbi.nlm.nih.gov/pubmed/20393565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08978
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