Identification of a Negative Allosteric Site on Human α4β2 and α3β4 Neuronal Nicotinic Acetylcholine Receptors

Acetylcholine-based neurotransmission is regulated by cationic, ligand-gated ion channels called nicotinic acetylcholine receptors (nAChRs). These receptors have been linked to numerous neurological diseases and disorders such as Alzheimer's disease, Parkinson's disease, and nicotine addic...

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Bibliographic Details
Main Authors: Pavlovicz, Ryan E., Henderson, Brandon J., Bonnell, Andrew B., Boyd, R. Thomas, McKay, Dennis B., Li, Chenglong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174232/
https://ncbi.nlm.nih.gov/pubmed/21949802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024949
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