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Transcription-induced DNA toxicity at trinucleotide repeats: Double bubble is trouble

Trinucleotide repeats (TNRs) are a blessing and a curse. In coding regions, where they are enriched, short repeats offer the potential for continuous, rapid length variation with linked incremental changes in the activity of the encoded protein, a valuable source of variation for evolution. But at t...

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書目詳細資料
Main Authors: Lin, Yunfu, Wilson, John H
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173998/
https://ncbi.nlm.nih.gov/pubmed/21293182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.4.14729
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