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Transcription-induced DNA toxicity at trinucleotide repeats: Double bubble is trouble
Trinucleotide repeats (TNRs) are a blessing and a curse. In coding regions, where they are enriched, short repeats offer the potential for continuous, rapid length variation with linked incremental changes in the activity of the encoded protein, a valuable source of variation for evolution. But at t...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173998/ https://ncbi.nlm.nih.gov/pubmed/21293182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.4.14729 |
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