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Fanconi anemia pathway regulates convergent transcription-induced cell death at trinucleotide repeats in human cells

Almost 20 incurable neurodegenerative disorders are caused by trinucleotide repeat (TNR) expansion beyond a certain threshold, with disease time of onset and severity positively correlating with repeat length. Typically, long TNRs display a bias toward further expansion and repeats continue to expan...

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Détails bibliographiques
Publié dans:Postdoc J
Auteurs principaux: Chatterjee, Nimrat, Lin, Yunfu, Wilson, John H.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006624/
https://ncbi.nlm.nih.gov/pubmed/27595121
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