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Mismatch repair enhances convergent transcription-induced cell death at trinucleotide repeats by activating ATR
Trinucleotide repeat (TNR) expansion beyond a certain threshold results in some 20 incurable neurodegenerative disorders where disease anticipation positively correlates with repeat length. Long TNRs typically display a bias toward further expansion during germinal transmission from parents to offsp...
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| Publicat a: | DNA Repair (Amst) |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889435/ https://ncbi.nlm.nih.gov/pubmed/27131875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.03.016 |
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