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Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway
The Fanconi anemia (FA) pathway is essential for the repair of DNA interstrand cross-links. At the heart of this pathway is the monoubiquitination of the FANCI-FANCD2 (ID) complex by the multiprotein “core complex” containing the E3 ubiquitin ligase FANCL. Vertebrate organisms have the eight-protein...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173227/ https://ncbi.nlm.nih.gov/pubmed/21775430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244632 |
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