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Towards a Molecular Understanding of the Fanconi Anemia Core Complex

Fanconi Anemia (FA) is a genetic disorder characterized by the inability of patient cells to repair DNA damage caused by interstrand crosslinking agents. There are currently 14 verified FA genes, where mutation of any single gene prevents repair of DNA interstrand crosslinks (ICLs). The accumulation...

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Detalles Bibliográficos
Main Authors: Hodson, Charlotte, Walden, Helen
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364535/
https://ncbi.nlm.nih.gov/pubmed/22675617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/926787
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