Modularized Functions of the Fanconi Anemia Core Complex

The Fanconi Anemia (FA) core complex provides the essential E3 ligase function for the FA pathway activation through the spatially defined FANCD2 ubiquitination. Of the seven FA gene products forming the core complex, FANCL possesses a RING domain with demonstrated E3 ligase activity. The other six...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Huang, Yaling, Leung, Justin WC, Lowery, Megan, Matsushita, Nobuko, Wang, Yucai, Shen, Xi, Huong, Do, Takata, Minoru, Chen, Junjie, Li, Lei
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157997/
https://ncbi.nlm.nih.gov/pubmed/24910428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.029
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