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Towards a Molecular Understanding of the Fanconi Anemia Core Complex

Fanconi Anemia (FA) is a genetic disorder characterized by the inability of patient cells to repair DNA damage caused by interstrand crosslinking agents. There are currently 14 verified FA genes, where mutation of any single gene prevents repair of DNA interstrand crosslinks (ICLs). The accumulation...

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Autors principals: Hodson, Charlotte, Walden, Helen
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364535/
https://ncbi.nlm.nih.gov/pubmed/22675617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/926787
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