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Ligand-switchable Substrates for a Ubiquitin-Proteasome System

Cellular maintenance of protein homeostasis is essential for normal cellular function. The ubiquitin-proteasome system (UPS) plays a central role in processing cellular proteins destined for degradation, but little is currently known about how misfolded cytosolic proteins are recognized by protein q...

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Detalhes bibliográficos
Main Authors: Egeler, Emily L., Urner, Lorenz M., Rakhit, Rishi, Liu, Corey W., Wandless, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173072/
https://ncbi.nlm.nih.gov/pubmed/21768107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.264101
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