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Dependence of Proteasome Processing Rate on Substrate Unfolding
Protein degradation by eukaryotic proteasomes is a multi-step process involving substrate recognition, ATP-dependent unfolding, translocation into the proteolytic core particle, and finally proteolysis. To date, most investigations of proteasome function have focused on the first and the last steps...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093823/ https://ncbi.nlm.nih.gov/pubmed/21454622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212027 |
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