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Dependence of Proteasome Processing Rate on Substrate Unfolding

Protein degradation by eukaryotic proteasomes is a multi-step process involving substrate recognition, ATP-dependent unfolding, translocation into the proteolytic core particle, and finally proteolysis. To date, most investigations of proteasome function have focused on the first and the last steps...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Henderson, Allen, Erales, Jenny, Hoyt, Martin A., Coffino, Philip
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093823/
https://ncbi.nlm.nih.gov/pubmed/21454622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212027
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