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Interaction of Thrombin with Sucrose Octasulfate

The serine protease thrombin plays multiple roles in many important physiological processes, especially coagulation, where it functions as both a pro- and anti-coagulant. The polyanionic glycosaminoglycan heparin modulates thrombin’s activity through binding at exosite II. Sucrose octasulfate (SOS)...

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Detalhes bibliográficos
Main Authors: Desai, Bijoy J., Boothello, Rio S., Mehta, Akul Y., Scarsdale, J. Neel, Wright, H. Tonie, Desai, Umesh R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172994/
https://ncbi.nlm.nih.gov/pubmed/21736375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2004526
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