Contributions of Human Cytochrome P450 Enzymes to Glyburide Metabolism

Glyburide (GLB) is a widely used oral sulfonylurea for the treatment of gestational diabetes. Therapeutic use of GLB is often complicated by a substantial inter-individual variability in the pharmacokinetics and pharmacodynamics of the drug in human populations, which might be caused by inter-indivi...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhou, Lin, Naraharisetti, Suresh B., Liu, Li, Wang, Honggang, Lin, Yvonne S., Isoherranen, Nina, Unadkat, Jashvant D., Hebert, Mary F., Mao, Qingcheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172044/
https://ncbi.nlm.nih.gov/pubmed/20437462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.706
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