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Validation of a sensitive LC-MS assay for quantification of glyburide and its metabolite 4-transhydroxy glyburide in plasma and urine: an OPRU Network study

Glyburide (glibenclamide, INN), a second generation sulfonylurea is widely used in the treatment of gestational diabetes mellitus (GDM). None of the previously reported analytical methods provide adequate sensitivity for the expected sub-nanogram/mL maternal and umbilical cord plasma concentrations...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Naraharisetti, Suresh Babu, Kirby, Brian J., Hebert, Mary F., Easterling, Thomas R., Unadkat, Jashvant D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696259/
https://ncbi.nlm.nih.gov/pubmed/17980680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2007.10.010
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