Quantitative determination of metformin, glyburide and its metabolites in plasma and urine of pregnant patients by LC-MS/MS

This report describes the development and validation of an LC-MS/MS method for the quantitative determination of glyburide (GLB), its five metabolites (M1, M2a, M2b, M3, and M4) and metformin (MET) in plasma and urine of pregnant patients under treatment with a combination of the two medications. Th...

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Detalhes bibliográficos
Publicado no:Biomed Chromatogr
Main Authors: Zhang, Xing, Wang, Xiaoming, Vernikovskaya, Daria I., Fokina, Valentina M., Nanovskaya, Tatiana N., Hankins, Gary D.V., Ahmed, Mahmoud S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344438/
https://ncbi.nlm.nih.gov/pubmed/25164921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.3314
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