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Quantitative determination of pravastatin and its metabolite 3α-hydroxy pravastatin in plasma and urine of pregnant patients by LC-MS/MS

This report describes the development and validation of a chromatography/tandem mass spectrometry method for the quantitative determination of pravastatin and its metabolite (3α-hydroxy pravastatin) in plasma and urine of pregnant patients under treatment with pravastatin, as part of a clinical tria...

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Detalhes bibliográficos
Publicado no:Biomed Chromatogr
Main Authors: Zhang, Xing, Vernikovskaya, Daria I., Wang, Xiaoming, Nanovskaya, Tatiana N., Costantine, Maged, Hankins, Gary D.V., Ahmed, Mahmoud S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744801/
https://ncbi.nlm.nih.gov/pubmed/26360932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.3581
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