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Role of human placental apical membrane transporters in the efflux of glyburide, rosiglitazone, and metformin

OBJECTIVE: Substrates of placental efflux transporters could compete for a single transporter, which could result in an increase in the transfer of each substrate to the fetal circulation. Our aim was to determine the role of placental transporters in the biodisposition of oral hypoglycemic drugs th...

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Detalhes bibliográficos
Main Authors: HEMAUER, Sarah J., PATRIKEEVA, Svetlana L., NANOVSKAYA, Tatiana N., HANKINS, Gary D.V., AHMED, Mahmoud S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848180/
https://ncbi.nlm.nih.gov/pubmed/20350646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2010.01.035
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