Selective regulation of Bcl-X(L) by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies

Bcl-2 family proteins are key regulators of apoptosis and function as cell death antagonists (e.g., Bcl-2, Bcl-X(L), and Mcl-1) or agonists (e.g., Bax, Bad, and Bak). Here we report that among the Bcl-2 family of proteins tested (Bcl-2, Bcl-X(L), Mcl-1, Bax, Bad, and Bak), Bcl-X(L) was unique in tha...

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Detalhes bibliográficos
Main Authors: Packham, Graham, White, Elsie L., Eischen, Christine M., Yang, Hui, Parganas, Evan, Ihle, James N., Grillot, Didier A.M., Zambetti, Gerard P., Nuñez, Gabriel, Cleveland, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317092/
https://ncbi.nlm.nih.gov/pubmed/9716401
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