Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis

Babesiosis is a tick-borne disease caused by eukaryotic Babesia parasites which are morphologically similar to Plasmodium falciparum, the causative agent of malaria in humans. Like Plasmodium, different species of Babesia are tuned to infect different mammalian hosts, including rats, dogs, horses an...

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Main Authors: Begley, Darren W., Edwards, Thomas E., Raymond, Amy C., Smith, Eric R., Hartley, Robert C., Abendroth, Jan, Sankaran, Banumathi, Lorimer, Donald D., Myler, Peter J., Staker, Bart L., Stewart, Lance J.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2011
Teme:
Structural Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169404/
https://ncbi.nlm.nih.gov/pubmed/21904052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111029009
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