Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis

Babesiosis is a tick-borne disease caused by eukaryotic Babesia parasites which are morphologically similar to Plasmodium falciparum, the causative agent of malaria in humans. Like Plasmodium, different species of Babesia are tuned to infect different mammalian hosts, including rats, dogs, horses an...

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Detalhes bibliográficos
Main Authors: Begley, Darren W., Edwards, Thomas E., Raymond, Amy C., Smith, Eric R., Hartley, Robert C., Abendroth, Jan, Sankaran, Banumathi, Lorimer, Donald D., Myler, Peter J., Staker, Bart L., Stewart, Lance J.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Structural Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169404/
https://ncbi.nlm.nih.gov/pubmed/21904052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111029009
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