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Substrate channeling between the human dihydrofolate reductase and thymidylate synthase

In vivo, as an advanced catalytic strategy, transient non‐covalently bound multi‐enzyme complexes can be formed to facilitate the relay of substrates, i. e. substrate channeling, between sequential enzymatic reactions and to enhance the throughput of multi‐step enzymatic pathways. The human thymidyl...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Protein Sci
Päätekijät: Wang, Nuo, McCammon, J. Andrew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815301/
https://ncbi.nlm.nih.gov/pubmed/26096018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2720
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