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Accurate and Sensitive Detection of Plasmodium Species in Humans by Use of the Dihydrofolate Reductase-Thymidylate Synthase Linker Region

A nested-PCR protocol based on the linker region of the Plasmodium dihydrofolate reductase-thymidylate synthase gene (dhfr-ts) was developed. This provides highly sensitive specific detection and identification of the five parasite species that infect humans.

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Autores principales: Tanomsing, Naowarat, Imwong, Mallika, Theppabutr, Sasikrit, Pukrittayakamee, Sasithon, Day, Nicholas P. J., White, Nicholas J., Snounou, Georges
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953080/
https://ncbi.nlm.nih.gov/pubmed/20702666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00898-10
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