Genetic Analysis of the Dihydrofolate Reductase-Thymidylate Synthase Gene from Geographically Diverse Isolates of Plasmodium malariae

Plasmodium malariae, the parasite responsible for quartan malaria, is transmitted in most areas of malaria endemicity and is associated with significant morbidity. The sequence of the gene coding for the enzyme dihydrofolate reductase-thymidylate synthase (DHFR-TS) was obtained from field isolates o...

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Detalhes bibliográficos
Main Authors: Tanomsing, Naowarat, Imwong, Mallika, Pukrittayakamee, Sasithon, Chotivanich, Kesinee, Looareesuwan, Sornchai, Mayxay, Mayfong, Dolecek, Christiane, Hien, Tran Tinh, do Rosario, Virgilio E., Arez, Ana Paula, Michon, Pascal, Snounou, Georges, White, Nicholas J., Day, Nicholas P. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043249/
https://ncbi.nlm.nih.gov/pubmed/17682097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00234-07
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