Genetic Analysis of the Dihydrofolate Reductase-Thymidylate Synthase Gene from Geographically Diverse Isolates of Plasmodium malariae

Plasmodium malariae, the parasite responsible for quartan malaria, is transmitted in most areas of malaria endemicity and is associated with significant morbidity. The sequence of the gene coding for the enzyme dihydrofolate reductase-thymidylate synthase (DHFR-TS) was obtained from field isolates o...

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Autores principales: Tanomsing, Naowarat, Imwong, Mallika, Pukrittayakamee, Sasithon, Chotivanich, Kesinee, Looareesuwan, Sornchai, Mayxay, Mayfong, Dolecek, Christiane, Hien, Tran Tinh, do Rosario, Virgilio E., Arez, Ana Paula, Michon, Pascal, Snounou, Georges, White, Nicholas J., Day, Nicholas P. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043249/
https://ncbi.nlm.nih.gov/pubmed/17682097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00234-07
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