Genetic Analysis of the Dihydrofolate Reductase-Thymidylate Synthase Gene from Geographically Diverse Isolates of Plasmodium malariae

Plasmodium malariae, the parasite responsible for quartan malaria, is transmitted in most areas of malaria endemicity and is associated with significant morbidity. The sequence of the gene coding for the enzyme dihydrofolate reductase-thymidylate synthase (DHFR-TS) was obtained from field isolates o...

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Hauptverfasser: Tanomsing, Naowarat, Imwong, Mallika, Pukrittayakamee, Sasithon, Chotivanich, Kesinee, Looareesuwan, Sornchai, Mayxay, Mayfong, Dolecek, Christiane, Hien, Tran Tinh, do Rosario, Virgilio E., Arez, Ana Paula, Michon, Pascal, Snounou, Georges, White, Nicholas J., Day, Nicholas P. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043249/
https://ncbi.nlm.nih.gov/pubmed/17682097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00234-07
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