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Cell cycle– and cell growth–regulated proteolysis of mammalian CDC6 is dependent on APC–CDH1
CDC6 is conserved during evolution and is essential and limiting for the initiation of eukaryotic DNA replication. Human CDC6 activity is regulated by periodic transcription and CDK-regulated subcellular localization. Here, we show that, in addition to being absent from nonproliferating cells, CDC6...
Uloženo v:
| Vydáno v: | Genes Dev |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316932/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10995389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.832500 |
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