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E2F1 is crucial for E2F-dependent apoptosis

Loss of the retinoblastoma protein, pRB, leads to apoptosis, and several results have suggested that this is dependent on the E2F transcription factors. However, so far, the ability of the different E2F family members to contribute to apoptosis is controversial. Here, we show that ectopic expression...

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Bibliographic Details
Main Authors: Lazzerini Denchi, Eros, Helin, Kristian
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369111/
https://ncbi.nlm.nih.gov/pubmed/15976820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400452
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