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E2F1 is crucial for E2F-dependent apoptosis

Loss of the retinoblastoma protein, pRB, leads to apoptosis, and several results have suggested that this is dependent on the E2F transcription factors. However, so far, the ability of the different E2F family members to contribute to apoptosis is controversial. Here, we show that ectopic expression...

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Detalhes bibliográficos
Main Authors: Lazzerini Denchi, Eros, Helin, Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369111/
https://ncbi.nlm.nih.gov/pubmed/15976820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400452
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