Cell cycle– and cell growth–regulated proteolysis of mammalian CDC6 is dependent on APC–CDH1

CDC6 is conserved during evolution and is essential and limiting for the initiation of eukaryotic DNA replication. Human CDC6 activity is regulated by periodic transcription and CDK-regulated subcellular localization. Here, we show that, in addition to being absent from nonproliferating cells, CDC6...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Petersen, Birgit Otzen, Wagener, Christian, Marinoni, Federica, Kramer, Edgar R., Melixetian, Marina, Denchi, Eros Lazzerini, Gieffers, Christian, Matteucci, Cristian, Peters, Jan-Michael, Helin, Kristian
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2000
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC316932/
https://ncbi.nlm.nih.gov/pubmed/10995389
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