Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export

Npl3p, the major mRNA-binding protein of the yeast Saccharomyces cerevisiae shuttles between the nucleus and the cytoplasm. A single amino acid change in the carboxyl terminus of Npl3p (E409 → K) renders the mutant protein largely cytoplasmic because of a delay in its import into the nucleus. This i...

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Pubblicato in:	Genes Dev
Autori principali:	Krebber, Heike, Taura, Tetsuya, Lee, Margaret S., Silver, Pamela A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 1999
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10444597/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.15.1994
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