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Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export
Npl3p, the major mRNA-binding protein of the yeast Saccharomyces cerevisiae shuttles between the nucleus and the cytoplasm. A single amino acid change in the carboxyl terminus of Npl3p (E409 → K) renders the mutant protein largely cytoplasmic because of a delay in its import into the nucleus. This i...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316916/ https://ncbi.nlm.nih.gov/pubmed/10444597 |
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