Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export
Npl3p, the major mRNA-binding protein of the yeast Saccharomyces cerevisiae shuttles between the nucleus and the cytoplasm. A single amino acid change in the carboxyl terminus of Npl3p (E409 → K) renders the mutant protein largely cytoplasmic because of a delay in its import into the nucleus. This i...
Shranjeno v:
| izdano v: | Genes Dev |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10444597/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.15.1994 |
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