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Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export

Npl3p, the major mRNA-binding protein of the yeast Saccharomyces cerevisiae shuttles between the nucleus and the cytoplasm. A single amino acid change in the carboxyl terminus of Npl3p (E409 → K) renders the mutant protein largely cytoplasmic because of a delay in its import into the nucleus. This i...

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Détails bibliographiques
Auteurs principaux: Krebber, Heike, Taura, Tetsuya, Lee, Margaret S., Silver, Pamela A.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC316916/
https://ncbi.nlm.nih.gov/pubmed/10444597
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