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Assessing Helical Protein Interfaces for Inhibitor Design
Structure-based design of synthetic inhibitors of protein-protein interactions requires adept molecular design and synthesis strategies as well as knowledge of targetable complexes. To address the significant gap between the elegant design of helix mimetics and their sporadic use in biology, we anal...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3168723/ https://ncbi.nlm.nih.gov/pubmed/21846146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja206074j |
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