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Contemporary Strategies for the Stabilization of Peptides in the α-Helical Conformation
Herein we review contemporary synthetic and protein design strategies to stabilize the α-helical motif in short peptides and miniature proteins. Advances in organometallic catalyst design, specifically for the olefin metathesis reaction, enable the use of hydrocarbon bridges to either crosslink side...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650020/ https://ncbi.nlm.nih.gov/pubmed/18793750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2008.08.019 |
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