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A Hydrogen Bond Surrogate Approach for Stabilization of Short Peptide Sequences in α-Helical Conformation
α-Helices constitute the largest class of protein secondary structures and play a major role in mediating protein-protein interactions. Development of stable mimics of short α-helices would be invaluable for inhibition of protein—protein interactions. This Account describes our efforts in developing...
שמור ב:
| הוצא לאור ב: | Acc Chem Res |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7189275/ https://ncbi.nlm.nih.gov/pubmed/18630933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar700264k |
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