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Solid-phase synthesis of short α-helices stabilized by the hydrogen bond surrogate approach

Stabilized α-helices and nonpeptidic helix mimetics have emerged as powerful molecular scaffolds for the discovery of protein–protein interaction inhibitors. Protein-protein interactions often involve large contact areas, which are often difficult for small molecules to target with high specificity....

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Protoc
Asıl Yazarlar: Patgiri, Anupam, Menzenski, Monica Z, Mahon, Andrew B, Arora, Paramjit S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575786/
https://ncbi.nlm.nih.gov/pubmed/21030960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2010.146
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