Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

SHIP is a 145-kD SH2-containing inositol-5-phosphatase widely expressed in hemopoietic cells. It was first identified as a tyrosine phosphoprotein associated with Shc in response to numerous cytokines. SHIP has been implicated in FcγRIIB receptor-mediated negative signaling in B cells and mast cells...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Helgason, Cheryl D., Damen, Jacqueline E., Rosten, Patty, Grewal, Rewa, Sorensen, Poul, Chappel, Suzanne M., Borowski, Anita, Jirik, Frank, Krystal, Gerald, Humphries, R. Keith
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1998
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9620849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.11.1610
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!