Protein Kinase C-δ Is a Negative Regulator of Antigen-Induced Mast Cell Degranulation

Regulation of mast cell degranulation is dependent on the subtle interplay of cellular signaling proteins. The Src homology 2 (SH2) domain-containing inositol-5′-phosphatase (SHIP), which acts as the gatekeeper of degranulation, binds via both its SH2 domain and its phosphorylated NPXY motifs to the...

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Autores principales: Leitges, Michael, Gimborn, Kerstin, Elis, Winfried, Kalesnikoff, Janet, Hughes, Michael R., Krystal, Gerald, Huber, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC133855/
https://ncbi.nlm.nih.gov/pubmed/12024011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.3970-3980.2002
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