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Protein Kinase C-δ Is a Negative Regulator of Antigen-Induced Mast Cell Degranulation

Regulation of mast cell degranulation is dependent on the subtle interplay of cellular signaling proteins. The Src homology 2 (SH2) domain-containing inositol-5′-phosphatase (SHIP), which acts as the gatekeeper of degranulation, binds via both its SH2 domain and its phosphorylated NPXY motifs to the...

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Publicat a:Mol Cell Biol
Autors principals: Leitges, Michael, Gimborn, Kerstin, Elis, Winfried, Kalesnikoff, Janet, Hughes, Michael R., Krystal, Gerald, Huber, Michael
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133855/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12024011/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.12.3970-3980.2002
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