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Cellular toxicity of expanded RNA repeats: focus on RNA foci

Discrete and punctate nuclear RNA foci are characteristic molecular hallmarks of pathogenesis in myotonic dystrophy type 1 and type 2. Intranuclear RNA inclusions of distinct morphology have also been found in fragile X-associated tremor ataxia syndrome, Huntington's disease-like 2, spinocerebe...

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Main Authors: Wojciechowska, Marzena, Krzyzosiak, Wlodzimierz J.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168290/
https://ncbi.nlm.nih.gov/pubmed/21729883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr299
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