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ADAM‐mediated amphiregulin shedding and EGFR transactivation
Introduction: The ectodomain shedding of epidermal growth factor receptor (EGFR) ligands, such as amphiregulin (AREG), by ADAMs (A Disintegrin And Metalloproteases) can be stimulated by G protein‐coupled receptor (GPCR) agonists. Interactions between the CXCR4 GPCR and the CXCL12 chemokine have bee...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3167473/ https://ncbi.nlm.nih.gov/pubmed/19735466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2009.00645.x |
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