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ADAM17 Transactivates EGFR Signaling during Embryonic Eyelid Closure
PURPOSE. During mammalian embryonic eyelid closure ADAM17 has been proposed to play a role as a transactivator of epidermal growth factor receptor (EGFR) signaling by shedding membrane bound EGFR ligands. However, ADAM17 also sheds numerous other ligands, thus implicating ADAM17 in additional molecu...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Association for Research in Vision and Ophthalmology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544417/ https://ncbi.nlm.nih.gov/pubmed/23211830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11130 |
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