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A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development

ADAM10 and ADAM17 are two closely related members of the ADAM (a disintegrin and metalloprotease) family of membrane-bound sheddases, which proteolytically cleave surface membrane proteins. Both ADAM10 and ADAM17 have been implicated in the proteolytic cleavage of NOTCH receptors and as such regulat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Toonen, Joseph A., Ronchetti, Adam, Sidjanin, D. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880208/
https://ncbi.nlm.nih.gov/pubmed/27224017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156184
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