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The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling

The disintegrin and metalloproteinase Adam10 has been implicated in the regulation of key signaling pathways that determine skin morphogenesis and homeostasis. To address the in vivo relevance of Adam10 in the epidermis, we have selectively disrupted Adam10 during skin morphogenesis and in adult ski...

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Detalles Bibliográficos
Main Authors: Weber, Silvio, Niessen, Michaela T., Prox, Johannes, Lüllmann-Rauch, Renate, Schmitz, Annika, Schwanbeck, Ralf, Blobel, Carl P., Jorissen, Ellen, de Strooper, Bart, Niessen, Carien M., Saftig, Paul
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014635/
https://ncbi.nlm.nih.gov/pubmed/21205794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.055210
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