The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling

The disintegrin and metalloproteinase Adam10 has been implicated in the regulation of key signaling pathways that determine skin morphogenesis and homeostasis. To address the in vivo relevance of Adam10 in the epidermis, we have selectively disrupted Adam10 during skin morphogenesis and in adult ski...

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Main Authors: Weber, Silvio, Niessen, Michaela T., Prox, Johannes, Lüllmann-Rauch, Renate, Schmitz, Annika, Schwanbeck, Ralf, Blobel, Carl P., Jorissen, Ellen, de Strooper, Bart, Niessen, Carien M., Saftig, Paul
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014635/
https://ncbi.nlm.nih.gov/pubmed/21205794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.055210
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