The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling

The disintegrin and metalloproteinase Adam10 has been implicated in the regulation of key signaling pathways that determine skin morphogenesis and homeostasis. To address the in vivo relevance of Adam10 in the epidermis, we have selectively disrupted Adam10 during skin morphogenesis and in adult ski...

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Detalhes bibliográficos
Main Authors: Weber, Silvio, Niessen, Michaela T., Prox, Johannes, Lüllmann-Rauch, Renate, Schmitz, Annika, Schwanbeck, Ralf, Blobel, Carl P., Jorissen, Ellen, de Strooper, Bart, Niessen, Carien M., Saftig, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014635/
https://ncbi.nlm.nih.gov/pubmed/21205794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.055210
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