Dual role of the Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes

Upon ligand binding, the receptors of the TGFβ family phosphorylate Smad proteins, which then move into the nucleus where they activate transcription. To carry out this function, the receptor-activated Smads 1 and 2 require association with the product of deleted in pancreatic carcinoma, locus 4 (DP...

Descripció completa

Dades bibliogràfiques

Publicat a:	Genes Dev
Autors principals:	Liu, Fang, Pouponnot, Celio, Massagué, Joan
Format:	Artigo
Idioma:	Inglês
Publicat:	Cold Spring Harbor Laboratory Press 1997
Matèries:	Research Paper
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9389648/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.23.3157
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!