Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor

Polarized epithelial non-human (canine) cell lines stably transfected with human or murine complementary DNA (cDNA) encoding for various efflux transporters (P-gp/MDR1, MRP1, MRP2, and Bcrp1) were used to study transepithelial transport of Lopinavir (LVR) and compare results with the MDCKII-Wild typ...

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Bibliographic Details
Main Authors:	Agarwal, Sheetal, Pal, Dhananjay, Mitra, Ashim K.
Format:	Artigo
Language:	Inglês
Published:	2007
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3166960/ https://ncbi.nlm.nih.gov/pubmed/17451894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2007.02.036
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Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor

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